Extremely Rare

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Being diagnosed with one of many very rare blood diseases can be scary and confusing. So much information is put into terms that is difficult to understand, which can leave you feeling lost and alone. But there are web sites that can help you to better understand your condition, and many that offer positive support through the process of treatment and recovery. One such site is mskcc dot org is one such site. Sloan-Kettering was developed to help cancer patients, but also offers valuable information for a variety of very rare blood diseases.

The site describes some rare forms of leukemias that many probably have never heard of. One such disease is Hairy Cell Leukemia, which attacks the cells that help create antibodies to fight infections. Signs of this disease include, abdominal pain, a low blood count, and the possibility of very rare infections, since the immune system is weakened so dramatically. Another rare form of blood cancer the site describes is Myleofibrosis, in which too much scar tissue is formed within the bone marrow. The presence of the tissue causes the red blood cells that pass through to be broken down.

In addition to these very rare blood diseases, information is also offered on eosinophilia, where a high number of eosinophils, which are a form of white blood cells, are present in the blood. Eosinophilia is not particularly a disease, but more a reaction to one. The body creates these extra cells to fight off an allergen, infection, or intrusive parasite, perhaps. When diagnosed with this condition, the underlying cause will be looked into next, to prevent a further complication from the actual disease that may not have shown signs yet.

Another one of the rare blood diseases that was described by Sloan-Kettering was paroxysmal nocturnal hemoglobinia. This disease starts with the mutation of stem cells in the bone marrow, which then causes red blood cells to break down as they pass through. In addition to this, platelets are not developed at a normal rate. This disease is treated in the same manner as aplastic anemia, but with a more aggressive approach. The disease can also be cured with a bone marrow transplant, which may be risky or appropriate, depending on the age and overall health of the patient.

Other very rare blood diseases include different types of hereditary anemias, idiopathic edema, congenital heart block, hereditary lymph edema, and vitamin B12 deficiency. These are just to name a few on the extensive list that is offered at bloodbook dot com. The site names a wide array of rare diseases and disorders that effect the blood, and gives a link to more information that is available on each disease. This site may be exceptionally helpful to any one who has been diagnosed and is looking for more clear information on a particular disease.

Ian Pennington is an accomplished niche website developer and author. To learn more about very rare blood diseases, please visit New Rare Diseases for current articles and discussions.

Brass Model Trains – Extremely Unique

For the ultimate collector “Brass Model Trains†may be the perfect choice. These toy model trains are made of solid brass and henceforth have an artistic quality to them. Due to the nature of the material the craftsmanship and uniqueness of the pieces are outstanding.  However, there is one slight drawback to the Brass Model Trains, the cost. The old saying “you get what you pay for†is not only fact but also the standard. Brass Model Trains are the “Gold†standard of toy model trains. Prices for these trains range upward to $2000 or more and raises the question of are these trains worth collecting. You are about to find out!

It is hard to say what is more important to a collector, appearance or resale value. Brass Model Trains have both. The quality of material, intricate detailing and overall appearance of these models gives the owner pride in the quality of their collection. Some trains in their natural color almost look as if they were made out of gold and that in turn keeps their resale value extremely high.  Due to the craftsmanship, look and cost of these toy model trains they are unique within a unique market. The model train collection market is a small niche but to be a niche within a niche makes the Brass Model Trains extremely rare and unique. Collectors like that aspect. The downside of collecting these unique trains is the cost. They can run more than twice the price of a standard composition train. If a collector wants a vintage brass model train he will pay even more than that since they are extremely rare.

Before you begin delving into these beautiful specimens consider the most important element of collecting brass model trains. Think about brass and how time and weather affects it. Now consider the value of your collection and the time and effort that it will require to properly clean, polish and protect your investment. If for some reason you are not able to give your collection enough care it will begin to turn black and on the other extreme, too much polishing will damage the collection. Caring for these pieces of art is a full time endeavor and requires a lot of work.

For many toy model trains enthusiast realism is the key to their entire collection. To the best of my knowledge there has never been a working locomotive that was made out of brass. So as interesting, valuable and decorative as these pieces are they are not typical of a working train and therefore not realistic. What you may want to consider is adding a piece or two of brass model trains to your collection as basically pieces of art to be showcased in you office or home while using a more traditional approach to your toy model train collection. Of course this really depend on what your purpose in collecting the trains is all about. Many collectors like to purchase sets and pieces that never leave the box and are displayed and traded like commodities while other are more like me in that they prefer to build lavish model train scenery layouts that consist of cities, switching yards, trains stations, mountain, etc.  Brass Model Trains are very unique and it really depends on the collector’s personality and intentions of whether these models will be a good fit. To each his own, as they say.

By the way, I own one and it is proudly displayed in my office!

About the Author

Michael Weston is a Model Train Expert with over 25 years of collecting experience and has a free special report that he wants to give to you called “7 Model Train Mistakes To Avoid.†For more information on toy model trains and the special report, visit http://www.modeltrainsexpert.com

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Paralysis from a stroke: Rare nerve transfer improves mobility
The Plastic Surgery Center today announced the successful results of a rare nerve transfer performed for the first known time on a stroke patient to reverse paralysis. Following the procedure, which was led by Dr. Andrew Elkwood, M.D., 47-year old Vincent Filipini is now able to lift, move and bend his once paralyzed arm. Mr. Filipini continues to show improvement in his mobility.

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